Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Accuracy of DE and DTF in Prediction of Extubation Success Clinical Trial

Official title:

Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03480828
• Other study ID #: rea1
• Status: Completed
• First received: March 22, 2018
• Last updated: March 28, 2018
• Start date: April 1, 2017
• Est. completion date: December 31, 2017

Study information

• Verified date: March 2018
• Source: Mongi Slim Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.

Description:

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation.

Our study compared the utility of DTF and DE to predict extubation success.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: December 31, 2017
• Est. primary completion date: December 31, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation

• patients without history of neuromuscular disease, or severe chronic respiratory failure

Exclusion Criteria:

• patients who needed reintubation for upper airway obstruction or neurological or hemodynamic instability

Related Conditions & MeSH terms

• Accuracy of DE and DTF in Prediction of Extubation Success

Intervention

Diagnostic Test:
• comparaison between DE and DTF in prediction of extubation success
diaphragm ultrasound and measurement of DE and DTF in patients meeting all extubation criteria during spontaneous breathing trial

Locations

Country	Name	City	State
Tunisia	Mongi Slim Hospital	La Marsa	Tunis

Sponsors (1)

Lead Sponsor	Collaborator
Mongi Slim Hospital

Country where clinical trial is conducted

Tunisia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	extubation success	comparaison between DE and DTF values in successfully extubated patients	48 hours after extubation