Pancreatic Cancer or Distal CBD Cancer Clinical Trial
Official title:
Comparison Between Volatile Anesthetic-desflurane and Total Intravenous Anesthesia With Propofol and Remifentanil on Early Recovery Quality and Long Term Prognosis of Patients Undergoing Pancreatic Cancer and Common Bile Duct Cancer Surgery
Investigators asses whether there is any difference in short term recovery and long term prognosis according to the anesthetic method in patients who undergoing pancreatic cancer and bile duct cancer and undergoing surgery for PPPD or distal pancreatectomy.
| Status | Recruiting |
| Enrollment | 132 |
| Est. completion date | August 28, 2022 |
| Est. primary completion date | August 28, 2022 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 20 Years and older |
| Eligibility |
Inclusion Criteria: - Patients with ASA class I-III who are scheduled to undergo general anesthesia and who are diagnosed with pancreatic cancer or common bile duct cancer and who are scheduled for PPPD or distal pancreatectomy - patients who voluntarily agree to participate the clinical study after fully informed and understood about the study Exclusion Criteria: - there was distant metastasis at the time of diagnosis - history of drug adverse reaction or use of opioid or sedative drugs before the surgery - patients who can not communicate enough to answer the survey - obesity patients over BMI 30 - patient who are expected to maintain ventilator care on the first day of post operation due to the difficult to extubation right after the surgery - patients who have inappropriate reasons to participate in clinical research |
| Country | Name | City | State |
|---|---|---|---|
| Korea, Republic of | Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University College of Medicine | Seoul |
| Lead Sponsor | Collaborator |
|---|---|
| Yonsei University |
Korea, Republic of,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | score of QoR40 (Quality of Recovery 40) | The QoR-40 consists of a total of 40 questionnaires divided into five categories, it is considered to be the most appropriate index to measure the patient's integrated post operation recovery. Our primary outcome is the score of QoR-40 on the third day after surgery | post operative day #3 | |
| Secondary | score of QoR40 (Quality of Recovery 40) | post operative day #1 | ||
| Secondary | score of QoR40 (Quality of Recovery 40) | post operative day #7 |