Airway Complication of Anesthesia Clinical Trial
Official title:
Factors Determining End-tidal O2 Concentration in During Pre-oxygenation
Earlier studies has shown a correlation between older age and longer time for the rise in the end-tidal O2 concentration during pre-oxygenation. In this study the investigators aim to analyse this correlation more closely and investigate if the arterial partial pressure of oxygen (PaO2) as measured before the start of pre-oxygenation, with the patient breathing air, is a better predictor than age for estimating the time necessary for achieving the goal of pre-oxygenation.
Before induction of general anaesthesia pre-oxygenation is a recommended procedure to enhance the time available for solving a problem with the airway or intubation during induction. This can be accomplished by letting the patient breath normal tidal volumes with 100% oxygen for 3 to 5 minutes during pre-oxygenation. If there is airway closure during tidal volume breathing, pre-oxygenation needs longer time to achieve a maximum effect. Airway closure increases with advanced age and a few earlier studies has also shown a correlation between older age and longer time for the rise in the end-tidal O2 concentration during pre-oxygenation. Pre-oxygenation is a strongly recommended safety procedure before starting anaesthesia but has at least one major side affect: it is the main reason for the development of atelectasis in the lungs during anaesthesia. Atelectasis impairs oxygenation during anaesthesia and probably increase the risk for postoperative pulmonary complications. Postoperative complications are more common with advanced age and it is important to understand the mechanisms and risk factors involved. In this study, the investigators hypothesise that the PaO2 as measured before the start of pre-oxygenation, with the patient breathing air, is a better predictor than age for estimating the time necessary for achieving the goal of pre-oxygenation. If this assumption is correct it might have implication for how pre-oxygenation should be adjusted with advancing age. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04498598 -
Structural Modification In Supraglottic Airway Device
|
N/A | |
| Completed |
NCT04569539 -
The Effect of a Head Elevated Positioning Device on Position, Height and Depth of the Cricothyroid Membrane in Morbidly Obese Pregnant Women in the Third Trimester.
|
N/A | |
| Recruiting |
NCT05902013 -
Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation
|
N/A | |
| Recruiting |
NCT05657028 -
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
|
N/A | |
| Completed |
NCT04546087 -
Impact of Labor and Delivery on Ultrasound Measured Cricothyroid Membrane Depth and Height
|
N/A | |
| Completed |
NCT03723109 -
Airway Management During TCI vs RSI Anesthesia Induction
|
||
| Recruiting |
NCT05899868 -
Utilization of Airway Stabilizing Rod
|
N/A | |
| Completed |
NCT03613103 -
Airway Injuries After Intubation Using Videolaryngoscopy Versus Direct Laryngoscopy for Adult Patients Requiring Tracheal Intubation
|
N/A | |
| Terminated |
NCT03664700 -
Observational Study of the LMA Protector
|
||
| Completed |
NCT04138121 -
Impact of Change of Head and Neck Position on Cricothyroid Membrane Localization and Membrane Height in Parturient Patients
|
N/A | |
| Not yet recruiting |
NCT03361397 -
Effect of Nebulized Lidocaine on the Quality of Laryngeal Mask Airway Insertion
|
N/A | |
| Recruiting |
NCT03366311 -
TCHCCT-Zhong-Xing-Emergency-Department-airway
|
N/A | |
| Completed |
NCT04196582 -
LMA® Gastro Airway Versus Gastro-Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
|
N/A | |
| Completed |
NCT05769842 -
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
|
N/A | |
| Completed |
NCT05106478 -
AuraGain Performance in Lateral Position
|
||
| Completed |
NCT04677894 -
Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
|
||
| Completed |
NCT03547193 -
Two Neck Ultrasound Measurements as Predictors of Difficult Laryngoscopy
|
||
| Completed |
NCT04833166 -
Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient
|
N/A | |
| Recruiting |
NCT05680909 -
Evaluation of SaCo Videolaryngeal Mask Airway in Morbidly Obese
|
||
| Recruiting |
NCT06403696 -
Predicting Post-op Airway Complications in Pediatric Patients Using Ultrasonography
|