Environmental-Pollution-Related Condition Clinical Trial
Official title:
Potential Risk for Bacterial Contamination in Conventional Reused Ventilator Systems and Disposable Closed Ventilator-Suction Systems
Background: Few studies have investigated the difference of bacterial contamination between
conventional reused ventilator systems and disposable closed ventilator-suction systems. The
aim of this study was to investigate the bacterial contamination rates of the reused and
disposable ventilation systems, and the association between system disconnection and
bacterial contamination of ventilator systems.
Methods: The enrolled patients used a conventional reused ventilator system and a disposable
closed ventilator-suction system, respectively, for a week; specimens were then collected
from the ventilators' internal system to evaluate human and environmental bacterial
contamination. The sputum specimens from patients were also analyzed in this study.
Results: The detection rate of bacteria in the conventional reused ventilator system was
substantially higher than that in the disposable system. The inspiratory and expiratory limbs
of disposable closed ventilator-suction system had higher bacterial concentrations than the
conventional reused ventilator system. The bacterial concentration in the heated humidifier
(HH) of the reused system was significantly higher than that in the disposable system.
Positive associations existed among the bacterial concentrations at different locations in
the reused and disposable ventilator systems, respectively. The predominant bacteria
identified in the reused and disposable ventilator systems included Acinetobacter spp.,
Bacillus cereus, Elizabethkingia spp., Pseudomonas spp., and Stenotrophomonas (Xan)
maltophilia.
Conclusion: Both the reused and disposable ventilation systems had high bacterial
contamination rates after one week of use. Disconnection of the ventilator systems should be
avoided during system operation for decreasing the risks of environmental pollution and human
exposure, especially for the disposable system.
The intubated and mechanically ventilated patients were enrolled from the Intensive Care Unit of Chang Gung Memorial Hospital, Taiwan. The experimental study group was assigned to a disposable ventilator system combined with an auto-filled heated humidifier (HH), a closed suction catheter, and a closed aerosol therapy procedure with a valved T-adaptor. According to clinical commonly used system, the control study group was assigned to use with conventional reused ventilator system, combined with a manually filled HH, an open suction catheter, and a conventional aerosol therapy procedure. Every patient was use above both ventilator systems. ;
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