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Postoperative Residual Paralysis After Cardiac Surgery

Postoperative Residual Curarization Clinical Trial

Official title:
Is Postoperative Residual Curarisation Still an Issue at the Moment of Weaning of the ICU Patient Following Cardiac Surgery?

Clinical Trial Summary

The main objective of this study is to describe the incidence of postoperative residual paralysis (mean train-of-four <90%) when weaning from the ventilator in patients admitted to the Intensive Care Unit (ICU) after elective cardiac surgery. Train-of-four monitoring is a widely used term for the peripheral nerve stimulation used in neuromuscular blockade monitoring. When the patient is ready for weaning from the ventilator, an ICU doctor will perform a measurement of the train-of-four at the thumb with a neuromuscular transmission monitor. Every value below 90% will be considered as residual paralysis and treated appropriately by means of a reversal agent.

Clinical Trial Description

Postoperatively, in the ICU, readiness-for-weaning is based on ICU doctor-nurse-driven institutional weaning guidelines: 6 hours after arrival in the ICU, a patient who is normothermic, hemodynamically stable, has normal blood gasses and absence of residual bleeding. The ICU nurse caring for the patient will start weaning the patient from the ventilator, following these departmental guidelines. ;

Study Design

Related Conditions & MeSH terms

  • Delayed Emergence from Anesthesia
  • Postoperative Residual Curarization
Clinical Trial Details
NCT number NCT03291184
Study type Interventional
Source Onze Lieve Vrouw Hospital
Contact
Status Completed
Phase N/A
Start date September 4, 2017
Completion date March 8, 2018
View Details
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