Enhancement of the ADR During Colonoscopy Clinical Trial
Official title:
Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility
| Verified date | April 2020 |
| Source | Mayo Clinic |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The investigators hypothesize that spraying peppermint oil containing L-menthol onto the colonic mucosa during colonoscopy will relax smooth muscle allowing better colonic visualization.
| Status | Completed |
| Enrollment | 48 |
| Est. completion date | September 10, 2019 |
| Est. primary completion date | September 10, 2019 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 50 Years and older |
| Eligibility |
Inclusion Criteria: - Screening colonoscopy - Age 50 years and older - Able to give consent Exclusion Criteria: - No consent obtained or adult lacking capacity to consent - Do not reach cecum on colonoscopy - Renal impairment (defined as CrCl <30 ml/min) - Allergy to study peppermint oil solution - History of colon resection - Inflammatory bowel disease - Known colorectal neoplasia - Non-correctable coagulopathy - Pregnancy or lactating - Prisoners |
| Country | Name | City | State |
|---|---|---|---|
| United States | Mayo Clinic in Arizona | Scottsdale | Arizona |
| Lead Sponsor | Collaborator |
|---|---|
| Mayo Clinic |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Determination of Adenoma Detection Rate during Colonoscopy Procedure | 2 hours |