Bilateral Total Knee Arthroplasty Clinical Trial
Official title:
Efficacy of Pain Management in Different Concentrations of Bupivacaine in Periarticular Injection and Plasma Concentrations of Bupivacaine in Patients Undergoing Bilateral Knee Arthroplasty
To study efficacy of postoperative pain control of different concentrations of bupivacaine
for periarticular infiltration, part of multimodal analgesia, in bilateral total knee
arthroplasty.
To study plasma concentration of bupivacaine in patient who received spinal anesthesia and
single shot bilateral adductor canal block and periarticular infiltration with bupivacaine
for safety level.
Adequate postoperative pain control reduce postoperative morbidity, multimodal analgesia techniques is used for achieve this goal. multimodal analgesia for bilateral total knee arthroplasty are peripheral nerve block, periarticular infiltration, NSAIDs, gabapentins and others. patients undergoing bilateral total knee arthroplasty in siriraj hospital receive spinal anesthesia, single shot bilateral adductor canal block and bilateral periarticular infiltration with bupivacaine so patient receive a large dose of bupivacaine. the investigators study the efficacy of postoperative pain of reduced dose of bupivacaine for periarticular infiltration. and study plasma level of bupivacaine. ;
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