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Clinical Trial Summary

This dose-escalating study is to determine the safety, pharmacokinetics, and preliminary efficacy of venetoclax in combination with navitoclax and chemotherapy in adult and pediatric participants with relapsed/refractory acute lymphoblastic leukemia (ALL) or relapsed/refractory lymphoblastic lymphoma. A safety expansion cohort of approximately 20 patients may be enrolled in addition to the 50 participants in dose-escalation cohort.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03181126
Study type Interventional
Source AbbVie
Contact
Status Completed
Phase Phase 1
Start date November 27, 2017
Completion date November 14, 2020

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