Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length

Apparently Healthy People Aged 55 and Over Clinical Trial

Official title:

Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length: A Cross-sectional Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03151824
• Other study ID #: C 2013152(1112)
• Status: Completed
• Phase: N/A
• First received: May 11, 2017
• Last updated: May 11, 2017
• Start date: October 25, 2013
• Est. completion date: October 24, 2014

Study information

• Verified date: May 2017
• Source: Chung-Ang University Hosptial, Chung-Ang University College of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Quality of life (QoL) is an important factor for successful aging. Telomere length is an indicator of cellular aging and cumulative biological stress and is thus related to health status and survival. However, the relationship between QoL and telomere length has not yet been examined. In this study we investigated the relationship between leukocyte telomere length (LTL) and QoL.

However, the relationship between overall QoL and LTL has not previously been investigated. Therefore, this study was conducted to examine the relationship between LTL and QoL. QoL was measured by the Korean version of the 36-item short-form health survey (SF-36), which is a multidimensional scale consisting of subjective evaluation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 164
• Est. completion date: October 24, 2014
• Est. primary completion date: October 24, 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 55 Years and older

Eligibility

Inclusion Criteria:

• married couple

• apparently healthy subjects above 55 years

Exclusion Criteria:

• Subjects who had experienced hormone therapy

• Subjects who had been diagnosed with dementia, Parkinson's disease, stroke, ischemic heart disease, congestive heart failure, arrhythmia, depression, cancer, thyroid disorders, or chronic renal disease

Related Conditions & MeSH terms

• Apparently Healthy People Aged 55 and Over

Intervention

Other:
• quality of life
Quality of life which was measured by the Korean version of the 36-item short-form health survey (SF-36)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Jung-Ha Kim

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	leukocyte telomere length	Leukocyte telomere length was measured as telomere repeat copy number relative to single gene copy number by quantitative real-time PCR	8months