General Anesthesia Management in 15 Preterm Infant

Anesthesia Management of Premature Infants Clinical Trial

Official title:

General Anesthesia Management in 15 Preterm Infant Undergoing Diode Laser Photocoagulation for Retinopathy of Prematurity: A Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03044366
• Other study ID #: ASOZKAN-1
• Status: Completed
• Phase: N/A
• First received: December 1, 2016
• Last updated: February 7, 2017
• Start date: December 2016
• Est. completion date: January 2017

Study information

• Verified date: February 2017
• Source: Inonu University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Anesthesia management of preterm infants is challenging for the anesthesiologist. Because of rudimentary build, many medical and physical problems have shown in treatment of disease such as complications, airway problems, temperature disregulation and deficient drug metabolism. This retrospective study evaluates the perioperative management and postoperative course in premature infants undergoing diode laser photocoagulation (DLP) for retinopathy of prematurity (ROP).

Description:

Participants retrospectively investigate clinical data and anesthesia process of 15 preterm infant from anesthesia charts with ROP who underwent DLP between 2014 and 2016. This presented retrospective study was confirmed by the Institutional Clinical Research Ethics Board. Neonates burns under 30 weeks gestation and low birth weigh under 2000 g were admitted to the study. No infant were excluded from the study. Preterm infants were appreciated before surgery and informed consent was obtained form their parents. We recorded gestational age, American Society of Anesthesiologists (ASA) physical status scores, post-conceptual age, weight at birth and surgery, duration of anesthesia and surgery, blood glucose values at surgery, the management of airway, total hospital stay period, analgesia management, complications and comorbidities. Bradycardia ( <90 beats/mean), desaturation (SpO2 <90%) and arrhythmia were recorded. Electrocardiography (ECG), pulse oximetric saturation (SpO2), end-tidal carbon dioxide pressure, heart rate (HR) and body temperature were monitored in operating room. Topical 0.5% proparacaine eye drops were administered to all infants routinely. Anesthesia was induced with thiopental 6 mg kg-1 and fentanyl 1 µg kg-1 and it was maintained with 50% oxygen 50% air 1%-3% sevoflurane in all cases. Inhaled anesthetic agent was not preferred for induction of anesthesia because of causing hypotension. The premature infants were intubated by same experienced anesthesiologist. In all infants, were intubated the patients without muscle relaxant under spontaneous ventilation. Perioperative complications, blood glucose value, devices in airway management and extubation value were recorded. After surgery, extubation was performed when spontanea ventilation was enough and extubation was recorded. All infants were taken to newborn intensive care unit (NICU). Data are reported as mean ± standard deviation and percentage(%).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: January 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 1 Month

Eligibility

Inclusion Criteria:

• all preterm infants who was decided to apply ROP

Exclusion Criteria:

• No patient was excluded

Related Conditions & MeSH terms

• Anesthesia Management of Premature Infants
• Retinopathy of Prematurity

Intervention

Other:
• general anesthesia management of preterm infants
general anesthesia management of preterm infants

Locations

Country	Name	City	State
Turkey	Inonu University Medical Faculty	Malatya

Sponsors (1)

Lead Sponsor	Collaborator
Inonu University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the management of airway	the management of airway	up to 2 years
Primary	gestational age	gestational age	up to 2 years
Primary	American Society of Anesthesiologists physical status scores	American Society of Anesthesiologists physical status scores	up to 2 years
Primary	post-conceptual age	post-conceptual age	up to 2 years
Primary	weight at birth and surgery	weight at birth and surgery	up to 2 years
Primary	duration of anesthesia and surgery	duration of anesthesia and surgery	up to 2 years