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Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Endoscopic Retrograde Cholangiopancreatography Clinical Trial

Official title:
Role of Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Clinical Trial Summary

- The investigators evaluated the role of allopurinol in prevention of post-ERCP pancreatitis.

- 100 Egyptian patients who were candidates for ERCP were included and divided into two groups. Group 1 (study group) included 50 patients who received two doses of allopurinol 300 mg each, 15 hours and 3 hours before ERCP and Group 2 (control group) included 50 patients who did not receive allopurinol prophylaxis.

Clinical Trial Description

A diagnosis of procedure-related pancreatitis was based on an increased serum amylase level greater than three times the upper normal limits, associated with abdominal pain requiring analgesics and persisting for at least 24 hours after the procedure. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

  • Endoscopic Retrograde Cholangiopancreatography
  • Pancreatitis
Clinical Trial Details
NCT number NCT02992652
Study type Interventional
Source Ain Shams University
Contact
Status Completed
Phase N/A
Start date January 2011
Completion date December 2014
View Details
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