Transient Tachypnea of the Newborn Clinical Trial
Official title:
A Non-invasive Method To Rule Out Transient Tachypnea of the Newborn (TTN) : Pulmonary Artery Acceleration to Ejection Time Ratio
This study aims to find out whether diagnosis of Transient Tachypnea of the Newborn(TTN) can be predicted via evaluating pulmonary artery Doppler indices.
Transient Tachypnea of the Newborn(TTN) is the most common diagnosed disease in state of
neonatal respiratory distress. However there is not an adequate method to diagnose or rule
out TTN.
In several studies pulmonary artery Doppler indices are investigated as the possible
indicators of pulmonary function. As a result of these studies, physiological processes in
fetal lung maturation were established; pulmonary tissue impedance or resistance decreases
with increasing gestational age, leading to increased pulmonary blood flow. In a normal lung
maturation process the peak sistolic velocity is reached in midsystole, but in case of any
reason disturbing the nornal development process,the peak occurs earlier.
We suggested that TTN, which is a factor increasing pulmonary tissue impedance like
respiratory distress syndrome(RDS) and pulmonary hypoplasia, would change pulmonary
artery(PA) Doppler indices, thus by the way of evaluating pulmonary artery Doplerr indices,
we could predict possible diagnosis of TTN
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