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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT02952560
Other study ID # 11-0791-AE
Secondary ID
Status Completed
Phase N/A
First received October 31, 2016
Last updated December 4, 2017
Start date March 2012
Est. completion date June 2017

Study information

Verified date October 2016
Source University Health Network, Toronto
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Difficulty in managing the airway is the single most important cause of major anesthesia-related morbidity and mortality. The currently used clinical method of predicting airway difficulty used by anesthetists is limited and not very highly sensitive or specific. Any additional bedside method that increases its specificity and sensitivity would be valuable. This project is designed to study and measure the tongue thickness and oral cavity height by using an ultrasound scan and comparing them with the same measurements obtained by CT scan. These will also be compared to a more complicated measurements used in previous studies to investigate any correlation with the currently used clinical methods. This information will help us decide if ultrasound may help Anesthesiologists assess difficulties in airway management in a more accurate, precise and reliable simpler method.


Recruitment information / eligibility

Status Completed
Enrollment 24
Est. completion date June 2017
Est. primary completion date June 2017
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- Age between 18 to 80 Years

- Gender: Both males and females are eligible for the study

- ASA I-III

- Scheduled for CT-scan of the head and neck as part of medical investigation (for test validation part)

Exclusion Criteria:

- Volunteer/ patient refusal

- Language Barrier

- Known oropharyngeal, laryngeal or head and neck disease or cancers

- Multiple amalgam fillings of the teeth

- Past history of oral or head and neck surgical procedures

- Past history of burns or radiotherapy of the head and neck region

- Presence of any scars, sinuses, infection, swelling, cysts in the head and neck region

Study Design


Related Conditions & MeSH terms

  • Ultrasound Airway Imaging in Determining the Oral Cavity and Tongue Size

Intervention

Other:
Ultrasound scan
Ultrasound scanning examinations will be performed twice (pre-CT scan and post CT-scan). Each examination will be performed by two observers who are blinded to each other's measured values.Patients will be asked to place a small sip of water (20 mL)in their mouth and keep the mouth open during the imaging. A second ultrasound examination of each patient by the two observers will be performed after the CT-scan.

Locations

Country Name City State
Canada Princess Margaret Hospital Toronto Ontario

Sponsors (1)

Lead Sponsor Collaborator
University Health Network, Toronto

Country where clinical trial is conducted

Canada, 

References & Publications (4)

Lakhal K, Delplace X, Cottier JP, Tranquart F, Sauvagnac X, Mercier C, Fusciardi J, Laffon M. The feasibility of ultrasound to assess subglottic diameter. Anesth Analg. 2007 Mar;104(3):611-4. — View Citation

Savva D. Prediction of difficult tracheal intubation. Br J Anaesth. 1994 Aug;73(2):149-53. — View Citation

Tsui BC, Hui CM. Sublingual airway ultrasound imaging. Can J Anaesth. 2008 Nov;55(11):790-1. doi: 10.1007/BF03016357. — View Citation

Werner SL, Smith CE, Goldstein JR, Jones RA, Cydulka RK. Pilot study to evaluate the accuracy of ultrasonography in confirming endotracheal tube placement. Ann Emerg Med. 2007 Jan;49(1):75-80. Epub 2006 Oct 2. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Validity of the assumption that ratio of "tongue thickness/oral cavity height" is a good estimate of the ratio "tongue volume/oral cavity volume" as measured by CT scan. 2012-2013
Primary Validity of ultrasound measurement of the two airway parameters (tongue thickness and height of oral cavity) against CT measurements of the same parameters. 2012-2013
Secondary Reproducibility of the ultrasound measurements 2012-2013
Secondary Correlating ultrasound measured values with Mallampati scores 2012-2013