Risk Factors for Postoperative Nausea/Vomiting

Postoperative Nausea and Vomiting Clinical Trial

Official title:

Risk Factors for Postoperative Nausea/Vomiting After Implementation of Prophylaxis Guideline for High Risk Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02944942
• Other study ID #: HE571413
• Status: Completed
• Phase: N/A
• First received: October 25, 2016
• Last updated: February 28, 2017
• Start date: September 2016
• Est. completion date: February 2017

Study information

• Verified date: February 2017
• Source: Khon Kaen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

General anesthetic technique plays a key role in most surgical procedures. This technique has some complications especially postoperative nausea/vomiting (PONV). This complication can lead to serious problems. Department of Anesthesiology has developed and implemented a PONV prophylaxis guideline for high risk PONV patients but PONV still remains.

Description:

Objective: To identify risk factors for PONV after implementation of PONV prophylaxis guideline.

Methods: This will be a retrospective analytic study. Relevant clinical data from medical records of adult patients undergoing general anesthesia in Srinagarind Hospital from November 2014 to February 2015 will be used to identify relevant risk factors.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 400
• Est. completion date: February 2017
• Est. primary completion date: February 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• ASA classification I-III

Exclusion Criteria:

• Incomplete or illegible medical records

• Patients who underwent cardio-thoracic surgery

• Patient who had chronic treatment with antiemetic drugs

Related Conditions & MeSH terms

• Nausea
• Postoperative Nausea and Vomiting
• Vomiting

Intervention

Procedure:
• General anesthesia
Patients undergoing general anesthesia

Locations

Country	Name	City	State
Thailand	Srinagarind Hospital, Faculty of Medicine, Khon Kaen University	Khon Kaen

Sponsors (1)

Lead Sponsor	Collaborator
Khon Kaen University

Country where clinical trial is conducted

Thailand, 

References & Publications (5)

Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology. 1999 Sep;91(3):693-700. — View Citation

Blanc VF, Ruest P, Milot J, Jacob JL, Tang A. Antiemetic prophylaxis with promethazine or droperidol in paediatric outpatient strabismus surgery. Can J Anaesth. 1991 Jan;38(1):54-60. — View Citation

Chatterjee S, Rudra A, Sengupta S. Current concepts in the management of postoperative nausea and vomiting. Anesthesiol Res Pract. 2011;2011:748031. doi: 10.1155/2011/748031. — View Citation

Doubravska L, Dostalova K, Fritscherova S, Zapletalova J, Adamus M. Incidence of postoperative nausea and vomiting in patients at a university hospital. Where are we today? Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Mar;154(1):69-76. — View Citation

Jokinen J, Smith AF, Roewer N, Eberhart LH, Kranke P. Management of postoperative nausea and vomiting: how to deal with refractory PONV. Anesthesiol Clin. 2012 Sep;30(3):481-93. doi: 10.1016/j.anclin.2012.07.003. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative nausea and vomiting		through study completion, an average of 24 hours