Medication-related Osteonecrosis of the Jaw (MRONJ) Registry — MRONJ  

Bisphosphonate-Associated Osteonecrosis of the Jaw Clinical Trial

Official title: International, Multicenter, Prospective Registry to Collect Data of Treatment Patterns of Patients With Medication-related Osteonecrosis of the Jaw (MRONJ) and Their Outcome

Status Active, not recruiting

Clinical Trial Summary

Approximately 500 patients will be included in this patient registry. Data collection includes demographics, clinical data of underlying disease and use of bisphosphonates, denosumab and antiangiogenic drugs , degree and extension of osteonecrosis, osteonecrosis-specific treatment, outcomes and complications within 1 year after treatment.

Clinical Trial Description

Approximately 500 patients diagnosed with medication-related osteonecrosis of the jaw will be enrolled in the study. Patients will undergo standard (routine) of care treatment, either conservative or surgical or both, and followed up during one year after the initiation of the treatment. Treatment outcome (development of the condition), pain and complications will be collected and documented over the duration of the registry. ;

Related Conditions & MeSH terms

• Bisphosphonate-Associated Osteonecrosis of the Jaw
• Medication-related Osteonecrosis of the Jaw
• Osteonecrosis

• NCT number: NCT02932501
• Study type: Observational [Patient Registry]
• Source: AO Innovation Translation Center
• Status: Active, not recruiting
• Start date: August 14, 2017
• Completion date: April 2024