Functional Neurological Disorders Clinical Trial
Official title:
The Pathophysiology of Functional Neurological Disorders
Functional disorders, also called psychogenic or psychosomatic are very common, disabling and
their costs to society are immense.
Functional movement disorders are abnormal, involuntary movements, that are illogical in
terms of classic neurology. Intriguingly, they typically manifest when patients pay attention
to them and disappear with distraction.
The investigators aim to further the understanding of the pathophysiological mechanisms
underlying functional neurological disorders in order to improve treatment. In particular
they aim to understand the effect of attention on movement in general, on functional
neurological mechanisms and on the sense of agency (of subjective control) over a movement.
Patients with a functional neurological disorder, patients with an organic neurological
disorder and healthy participants will perform simple tasks, such as reaching to a target,
while additional tasks will manipulate their attention. The effects of these attentional
manipulations will be analysed on several levels: movement performance, analysed by the
kinematics and electromyography (EMG),and psychophysical measures, such as the sense of
agency.
If the hypothesis turns out to be true, then changing the attentional focus could be used as
a treatment in functional neurological disorders.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04662372 -
Functional Neurological Disorders in Patients Admitted in Stroke Units
|