Early Neonatal Respiratory Distress: Changes in Level IIb Hospital Over a Period of One Year — DROPE  

Neonatal Respiratory Distress Syndrome Clinical Trial

Official title: Early Neonatal Respiratory Distress: Changes in Level IIb Hospital Over a Period of One Year

Status Completed

Clinical Trial Summary

Respiratory distress is one of the first hospital grounds during the neonatal period. The clinical presentation and severity vary by gestational age and cause. She reports to various etiological factors as maternal, neonatal or sometimes entangled. The symptomatic management has benefited from organizational progress (perinatal care) and techniques, including antenatal steroids, the use of exogenous surfactant and non-invasive ventilation early, so that the use of intubation is less frequent. The short-term evolution of patients with early respiratory distress is based on gestational age, cause and initial management.

Clinical Trial Description

Main objective:

To describe the care and short-term respiratory become newborns 32 weeks gestation or older with early and persistent respiratory distress to 2 hours of life (H2) over a period of one year in a type IIb motherhood.

Methodology :

Design: retrospective, descriptive, single-center, non-interventional

Performed in the Saint Joseph neonatal unit. Study duration: 1 year (01/05/2013-04/30/2014).

Acquisition of data:

The patients were selected from the hospitalization reports of infants by taking the following key words: respiratory distress, invasive and noninvasive ventilation, intubation, exogenous surfactant, pneumothorax.

Data collected:

• Obstetric data:

• Mode of delivery: route of delivery, presentation at birth.

• Maternal morbidity.

• antenatal corticosteroids in infants less than 34 weeks.

• Neonatal data:

• Gestational Age

• Birth Weight

• cord pH

• Apgar M5

• The terms of the allocation:

• Tracheal Intubation

• ventilation modes (controlled mechanical ventilation (VMC), non-invasive ventilation (NIV), nasal cannula), the maximum reached FiO2 (fraction of inspired oxygen), ventilation time for each ventilation mode. These different methods were studied in the delivery room during hospitalization (in intensive care and neonatal intensive care "NICU").

• The place of hospitalization: resuscitation and / or NICU.

• The transfer to the NICU resuscitation if necessary.

• Received drugs (exogenous surfactant, antibiotics, caffeine)

• The successful primary diagnosis. ;

Related Conditions & MeSH terms

• Hyaline Membrane Disease
• Neonatal Respiratory Distress Syndrome
• Respiratory Distress Syndrome
• Respiratory Distress Syndrome, Newborn

• NCT number: NCT02824497
• Study type: Observational
• Source: Groupe Hospitalier Paris Saint Joseph
• Status: Completed
• Start date: May 2015
• Completion date: May 2015