Effect of Plasma Rich in Growth Factors on Semen Quality

Vascular Endothelial Growth Factor Overexpression Clinical Trial

Official title: Effect of Plasma Rich in Growth Factors (PRGF) on Semen Quality

Status Completed

Clinical Trial Summary

The hypothesis is growing semen samples with plasma rich in growth factors (PRGF), because it could improve sperm motility in patients subsidiary TRA, ultimately improving pregnancy rates.

Clinical Trial Description

Platelet growth factors are a group of proteins involved in cellular communication modifying biological responses. Obtaining plasma rich in growth factors is already widespread and simple protocol technique that is being used in various areas of medicine with superb results. Described many of the growth factors present in the PRGF are related to sperm parameters, especially motility The described effects have been studied in mammalian and each growth factor individually. PRGF contains a pool of growth factors and therefore be interesting to analyze their effect on various sperm parameters. One of those parameters is very important for fertilization sperm motility, since the lack of it will prevent displacement by the cervix to meet the egg in the fallopian tube. ;

Related Conditions & MeSH terms

• Vascular Endothelial Growth Factor Overexpression

• NCT number: NCT02708537
• Study type: Observational
• Source: IVI Bilbao
• Status: Completed
• Start date: April 2016
• Completion date: December 2017