Detection of Preeclampsia Complications Clinical Trial
— PETOfficial title:
Correlation Between Complications of Pre-eclampsia and Detection of Novel Biochemical Markers
| Verified date | June 2017 |
| Source | Assiut University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney
impairment characteristics, a recent study demonstrated that the serum levels of NGAL
increased at the end of the second trimester in women who subsequently developed
pre-eclampsia compared to the control group.
This correlates well with the endothelial damage that occurs during pre-eclampsia and thus
NGAL can be considered as a promising marker in predicting both early and late onset
pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the
precision, and sensitivity for detection of risk and reliability of using biomarkers for
pre-eclampsia.
| Status | Completed |
| Enrollment | 90 |
| Est. completion date | May 2017 |
| Est. primary completion date | December 2016 |
| Accepts healthy volunteers | No |
| Gender | Female |
| Age group | 20 Years to 40 Years |
| Eligibility |
Inclusion Criteria: - Age 20-40 years. - Gestational age >20 weeks. Exclusion Criteria: - Patients with preexisting renal disease,hypertension, diabetes mellitus, gestational hypertension. - Patients Refuse to participate in the study - Patients already have complicated preeclampsia. |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Ahmed Abbas | Assiut | Cairo |
| Lead Sponsor | Collaborator |
|---|---|
| Assiut University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | The level of circulating NGAL | 24 hours |