OBSESSIVE COMPULSIVE DISORDER (OCD) Clinical Trial
Official title:
The Resonance Assessment in Magnetic Measurement of the Effect of Psychotherapy in Obsessive-compulsive Disorder in a Randomized Clinical Trial
This is a sample made up of ninety-six adult individuals of both sexes to be divided into
three groups: the experimental group of thirty-two patients with OCD who will be undergone
Trial-Based Cognitive Therapy; the gold standard, with thirty-two people with OCD subject
Exposure and Response Prevention and the control group of thirty-two healthy individuals.
Interviews and therapeutic intervention occur in private practices researchers or medical
schools accredited by UESPI.
Experimental group: Will be eligible adults of both sexes with educational level equal to or
higher education complete primary, aged between 18 and 60 years with OCD diagnosis confirmed
according to criteria DSM-IV (APA, 1994). It is going to be excluded patients who had
previously undergone treatment behavioral psychotherapy or cognitive-behavioral approach.
OBJECTIVES
Evaluate the effectiveness of Trial-Based Cognitive Therapy (TBCT) compared to Exposure and
Response Prevention (ERP) in the treatment of OCD patients, by neuroimaging tests such as
MRI.
1. Describe the neuroanatomical profile of the sample participants before and after the
psychotherapeutic intervention by MRI;
2. Compare the profile neuroanatomical between the experimental group and the control
group by MRI;
3. Identify possible neuroanatomical differences in the participating sample of pre and
post-treatment, both among individuals and among psychotherapeutic intervention groups;
4. To investigate associations between the results of MRI scans and indexes the scales
currently used to assess severity of OCD.
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