Intrahepatic Cholestasis of Pregnancy Clinical Trial
Official title:
Diagnostic Accuracy of Serum Autotaxin Levels in Cholestasis of Pregnancy
Intrahepatic cholestasis of pregnancy is the most common liver disease in pregnancy. It is is a pregnancy-specific liver disorder with onset mainly in the third trimester of pregnancy. ICP is characterized by pruritus, elevated serum fasting bile salts and transaminases and an increased risk of adverse fetal outcomes. Serum autotaxin levels were found highly sensitive and specific biomarker to to differentiate ICP from other pregnancy-related liver disorders or pruritic dermatoses. The purpose of the study is to determine the diagnostic accuracy of serum autotaxin activity in cholestasis of pregnancy.
| Status | Recruiting |
| Enrollment | 50 |
| Est. completion date | January 2017 |
| Est. primary completion date | June 2016 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Female |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Clinical diagnosed cholestasis of pregnancy patients Exclusion Criteria: - acute or chronic liver disease - acute or chronic gallbladder disease |
Observational Model: Case Control, Time Perspective: Cross-Sectional
| Country | Name | City | State |
|---|---|---|---|
| Turkey | Sisli Etfal Training and Research Hospital | Istanbul |
| Lead Sponsor | Collaborator |
|---|---|
| Sisli Etfal Training & Research Hospital |
Turkey,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Serum autotaxin levels in cholestasis of pregnancy | one year | No |
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