Diagnostic Values of Lung Ultrasound for Perioperative Atelectasis

Postoperative Pulmonary Atelectasis Clinical Trial

Official title:

Diagnostic Performance of Lung Ultrasound for Perioperative Atelectasis in Adult Patients Undergoing General Anesthesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02355405
• Other study ID #: XY3-LUS-8711
• Status: Completed
• Phase: N/A
• First received: January 30, 2015
• Last updated: April 17, 2015
• Start date: January 2015
• Est. completion date: April 2015

Study information

• Verified date: April 2015
• Source: The Third Xiangya Hospital of Central South University
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

Lung ultrasound offers a novel, reliable and radiation-free tool for diagnosing perioperative atelectasis and evaluating its severity in adult patients undergoing general anesthesia in the operating room.

Description:

Atelectases occur in up to 90% of patients undergoing general anesthesia and intubation. The aim of the present observational study was designed to further to evaluate the diagnostic performance of lung ultrasound (LUS) in detection of postoperative atelectasis in adult patients undergoing general anesthesia. Results of LUS as the experimental method will be compared to the results of computed tomography (CT) as the reference technique for the detection of atelectasis. The investigators want to confirm former findings of the appearance of perioperative atelectases and to prove that ultrasound is a valid tool for detection of atelectases.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 46
• Est. completion date: April 2015
• Est. primary completion date: March 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Aged 18 years and older;

2. American Society of Anesthesiologists (ASA) physical status within class I-III;

3. Scheduled for selective neurosurgical operation with general anesthesia;

4. Need of mechanical ventilation more than 2 hours;

Exclusion Criteria:

1. Patients decline to participate;

2. Pregnancy;

3. Previous thoracic procedures (thoracic drain, thoracotomy, thoracoscopy);

4. A history of pulmonary diseases within last two weeks with abnormal manifestation of lung CT (pulmonary parenchyma or/and interstitial lesions );

5. Pneumothorax or subcutaneous emphysema during peri-operation;

6. Patients with a body mass index (BMI) more than 30 kg/m2;

7. Emergency operation.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Postoperative Pulmonary Atelectasis
• Pulmonary Atelectasis

Intervention

Device:
• lung ultrasound
lung ultrasound investigations were performed right before and after the surgical procedure.

Radiation:
• thoracic computed tomography
thoracic CT were performed within one hour after the LUS investigation

Locations

Country	Name	City	State
China	The Third Xiangya Hospital of Central South University	Changsha	Hunan
China	Xiangya Hospital of Central South University	Changsha	Hunan

Sponsors (2)

Lead Sponsor	Collaborator
The Third Xiangya Hospital of Central South University	Xiangya Hospital of Central South University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation between manifestations of atelectasis in lung ultrasound and in thoracic computed tomography.	Measurements of lung ultrasound are performed before induction of anesthesia and immediately after finishing the surgery. Lung CTs are performed the day before surgery and within 1 hour after surgery. Outcome measure: comparison of atelectases by lung ultrasound (experimental method) versus by computed tomography (standard method)	From 5 minutes before induction of anesthesia to 1 hour after the surgery	Yes