Acquired Nasolacrimal Duct Obstruction Clinical Trial
— ANLDOOfficial title:
To Estimate Whether Corneal Epithelial Defects Occur in Patients With Acquired Nasolacrimal Duct Obstructions is Linked to Changes Occurring Within Ocular Bacterial Flora in These Patients, and What Are the Specific Changes in Their Flora.
Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | February 2015 |
| Est. primary completion date | February 2015 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - 18 years of age or older, nasolacrimal duct obstruction Exclusion Criteria: - younger then 18 years of age - ocular infections - patients after repair of lacrimal duct surgery - systemic active diseases - patients taking medication that are know to influence bacterial flora of the eye |
Observational Model: Case Control, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Israel | Western Galileeh Hospital | Naharya |
| Lead Sponsor | Collaborator |
|---|---|
| Western Galilee Hospital-Nahariya |
Israel,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | the change of ocular normal flora in patients with nasolacrimal duct obstruction as a comparison to general population. | as the literature suggests most of the ocular flora is composed of Staphylococcus and Haemophilus, any change in these composition will be considered abnormal. | 6 month | No |