Adult Onset Growth Hormone Deficiency Clinical Trial
Official title:
Bone Geometry, Volumetric Density, Microarchitecture and Estimated Bone Strength Assessed by High Resolution Peripheral Quantitative Computed Tomography in Patients With Adult Onset Growth Hormone Deficiency
The aim of the study is to assess bone geometry, bone compartment specific volumetric densities and micro-architecture as well as to evaluate non-invasive estimates of bone strength in patients with adult onset growth hormone deficiency.
| Status | Not yet recruiting |
| Enrollment | 45 |
| Est. completion date | |
| Est. primary completion date | June 2015 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years to 80 Years |
| Eligibility |
Inclusion Criteria: - Men and women diagnosed with Adult onset Growth Hormone Deficiency - Age between 18-80 - Informed consent Exclusion Criteria: - Competing bone disease (e.g.. Mb. Paget, myelomatosis, osteogenesis imperfecta, osteoporosis, primary hyperparathyroidism) - Ongoing medical treatment affecting bone metabolism (eg. osteoporosis medications) - Ongoing pregnancy or breast feeding |
Observational Model: Case Control, Time Perspective: Cross-Sectional
| Country | Name | City | State |
|---|---|---|---|
| Denmark | Endocrinological department M, Odense University Hospital | Odense | Region syddanmark |
| Lead Sponsor | Collaborator |
|---|---|
| Odense University Hospital |
Denmark,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | volumetric bone mineral density in grams per cc | 1 year | No |