Continuous Versus Interval Walking Training in Patients With COPD - a Pilot Study

Chronic Obstructive Airway Disease Clinical Trial

Official title:

Continuous Versus Interval Walking Training in Patients With Severe Chronic Obstructive Pulmonary Disease - a Pilot Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02209207
• Other study ID #: Walking trial 2014
• Status: Completed
• Phase: N/A
• First received: July 31, 2014
• Last updated: February 23, 2016
• Start date: July 2014
• Est. completion date: November 2015

Study information

• Verified date: February 2016
• Source: Klinikum Berchtesgadener Land der Schön-Kliniken
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: ethic commissions
• Study type: Interventional

Clinical Trial Summary

This study will investigate the effects of interval walking training versus continuous walking training in patients with chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized to one of the two intervention groups. All walking training sessions will be performed on the same treadmill. Walking intensity in the continuous walking group will be 60 percent of the average speed of the 6-minute walking test. Patients in the interval training group will perform high intensity intervals at 120% of the 6-minute walking test speed for 60 seconds alternating with 60 seconds of rest. The total exercise duration will be progressively increased from 10 to 32 minutes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: November 2015
• Est. primary completion date: November 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• COPD stage III or IV according to the Global Initiative for chronic obstructive lung disease [GOLD]

• stationary patient in the Schön Klinik Berchtesgadener Land

Exclusion Criteria:

• acute, severe exacerbation of COPD

• failure to comply with study process

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Chronic Obstructive Airway Disease
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Device:
• Treadmill

Other:
• walking training

Locations

Country	Name	City	State
Germany	Schön Klinik Berchtesgadener Land	Schönau am Königssee

Sponsors (1)

Lead Sponsor	Collaborator
Klinikum Berchtesgadener Land der Schön-Kliniken

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	perceived exertion for dyspnea during walking training	measured via modified Borg scale (0 to 10)	day 1 to 21	No
Secondary	heart rate during walking training		day 1 to 21	No
Secondary	perceived exertion for leg fatigue (Borg-scale)		during three weeks of rehabilitation	No
Secondary	Oxygen saturation during walking training	measured via pulse oximeter	day 1 to 21	No
Secondary	fat free mass in kilogram	measured via Bioimpedance Analysis	day 1 to 21	No
Secondary	forced expiratory volume in 1 second (FEV1) in liter	measured by spirometry	day 1 to 21	No
Secondary	Sit-to-stand-test	5 repetitions of standing up and sitting down from a chair with crossed arms as quick as possible	day 1 to 21	No
Secondary	6-minute walking test	the best 6-minute walking test out of two tests on admission and at discharge will be taken	day 1 to 21	No
Secondary	36 item short-form health Survey (SF-36)	questionnaire for disease unspecific quality of life	day 1 to 21	No
Secondary	chronic respiratory questionnaire (CRQ)	disease specific quality of life questionnaire	day 1 to 21	No
Secondary	hospital anxiety and depression scale (HADS)	questionnaire on symptoms of anxiety and depression	day 1 to 21	No