Diagnostic and Monitoring Anesthesiology Devices Associated With Adverse Incidents Clinical Trial
Official title:
Using Non-invasive Near-infrared Spectroscopy and Color Doppler to Evaluate the Relationship Between the Perfusion of Uterus and Gastrocnemius Muscles of the Parturients Receiving Cesarean Section
NCT number | NCT02178774 |
Other study ID # | 201401059RIND |
Secondary ID | |
Status | Not yet recruiting |
Phase | N/A |
First received | June 23, 2014 |
Last updated | June 30, 2014 |
Start date | June 2014 |
Hypotension after spinal anesthesia for cesarean section is one of the most common perioperative issue, with an incidence up to 83%.Hypotension is mainly induced by the associated sympathetic blockade, with a drop of peripheral vascular resistance in the lower extremities and an increase in venous capacitance. Hypotension is a distress for both anesthesiologists and obstetricians as it endangers parturient's hemodynamics and compromises the uteroplacental blood flow. In clinical practice, there are several ways to treat hypotension after spinal anesthesia such as preloading with intravenous fluids and administrating ephedrine. Normotensive maternal blood pressure does neither guarantee the well-being of the fetus nor ensure the tissue perfusion of the parturient. Based on the anatomy and physiology basis, we hypothesize that uterine perfusion under spinal anesthesia would correlate with the perfusion of the lower extremities. To measure the perfusion of the lower extremities, we use a relative new tool, the non-invasive transcutaneous near infrared spectroscopy.
Status | Not yet recruiting |
Enrollment | 40 |
Est. completion date | |
Est. primary completion date | January 2015 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: - Parturients - elective cesarean section - ASA class I or class II Exclusion Criteria: - Emergent cesarean section - Skin lesions over the site of local anesthetic injection - Skin lesions over the sites where NIRS patches are about to be attached - Patients with history of being allergic to NIRS patches - Patients with coagulopathy or other contraindications for spinal anesthesia |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | tissue oxygen saturation | Tissue oximeter starts recording before and every minute right after local anesthetics are injected into the intrathecal space for a total of fifteen minutes. | No |