Downhill Walking Training in COPD

Pulmonary Disease, Chronic Obstructive Clinical Trial

Official title:

Downhill Walking to Enhance Training Effects in Patients With COPD

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02113748
• Other study ID #: ML10278
• Status: Recruiting
• Phase: N/A
• First received: April 8, 2014
• Last updated: April 11, 2014
• Start date: April 2014

Study information

• Verified date: April 2014
• Source: Katholieke Universiteit Leuven
• Contact: Thierry Troosters, PhD
• Email: Thierry.Troosters[@]kuleuven.be
• Is FDA regulated: No
• Health authority: Belgium: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD.

Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 42
• Est. primary completion date: April 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients with a primary diagnosis of COPD according to internationally accepted guidelines

• Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium)

Exclusion Criteria:

• Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities

• Absence of exacerbations in the previous month before entering the present study

• Patients included on the waiting list for lung transplantation

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Chronic Disease
• Lung Diseases
• Pulmonary Disease, Chronic Obstructive

Intervention

Other:
• Downhill walking training
Walk on a treadmill with a negative inclination.
• Conventional walking training
Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations

Locations

Country	Name	City	State
Belgium	University Hospitals Leuven	Leuven	Vl-Brabant

Sponsors (3)

Lead Sponsor	Collaborator
Katholieke Universiteit Leuven	Conselho Nacional de Desenvolvimento Científico e Tecnológico, Research Foundation Flanders

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in 6-minute walking distance		changes from baseline to Week 12	No