The Effect of Prednisone on Physical Exercise in COPD Patients

Exercise Performance in Copd Patients Clinical Trial

— COPDpred  

Official title:

The Effect of Prednisone and Solu-Medrol on Physical Exercise in COPD Patients and the Inflammaroty Response During and After Exercis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01978665
• Other study ID #: 2012-004503-13
• Secondary ID: 2012-004503-13
• Status: Completed
• Phase: Phase 4
• Start date: April 2013
• Est. completion date: December 2013

Study information

• Verified date: November 2013
• Source: Bispebjerg Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of this study is to investigate if there is an effect on exercise performance og of the anti inflammatory drugs prednisone and solu-medrol in patints with chronic obstructive pulmonary disease(COPD)

Description:

RCT study with 4 days of steroid

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: December 2013
• Est. primary completion date: December 2013
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:FEV1< 60% FEV1/FVC ratio <70 %

• able to use a ergometer bike

Exclusion Criteria: Haemodynamicaly unstable heart conditions

• exacerbations before 6 week entry of the study exacerbation during the study period treatment with beta blockers malignancy the last 5 years allergi toward IMP

Related Conditions & MeSH terms

• Exercise Performance in Copd Patients

Intervention

Drug:
• prednisone
similar size tablets

Locations

Country	Name	City	State
Denmark	Bispebjerg Hospital	Copenhagen	NV

Sponsors (1)

Lead Sponsor	Collaborator
Bispebjerg Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	vo2max	fitness	jan 2013 to july 2013 ( 6 months)
Other	VO2max	fitness	jan 2013 until july 2013 (6 months)
Primary	effect on muscle power	muscular strenght	jan 2013 to july 2013 (6 months)
Secondary	the inflammatory response	hsCRP	jan 2013 to july 2013 (6 months)