Influence of Pregnenolone on Exposure Therapy in Obsessive-compulsive Disorder — P-EX

Obsessive-compulsive Disorder (OCD) Clinical Trial

Official title:
Influence of Pregnenolone on Distress and Autonomic Parameters During Cognitive-behavioral Exposure Therapy in Patients With Obsessive-compulsive Disorder

Status Recruiting

Clinical Trial Summary

Characterization of the influence of pregnenolone vs. placebo on subjective distress and autonomic functioning during cognitive-behavioral exposure therapy in patients with obsessive-compulsive disorder.

Clinical Trial Description

Main out-come parameters:

Inter-session habituation as per SUD (100 mm VAS), Y-BOCS

Secondary out-come parameter:

HF/LF of HRV, Salivary epinephrine ;

Study Design

Related Conditions & MeSH terms

Disease
Obsessive-Compulsive Disorder
Obsessive-compulsive Disorder (OCD)

Clinical Trial Details

NCT number	NCT01949753
Study type	Interventional
Source	Universitätsklinikum Hamburg-Eppendorf
Contact	Michael Kellner, MD, PhD
Email	kellner@uke.uni-hamburg.de
Status	Recruiting
Phase	Phase 2
Start date	September 2013
Completion date	December 2018

View Details

See also
Status	Clinical Trial	Phase
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Completed	`NCT02867449` - Metacognitive Therapy for Obsessive-Compulsive Disorder	N/A
Completed	`NCT01368510` - Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder	N/A
Not yet recruiting	`NCT05422469` - OCD Biomarker Survey Employing sEEG and Stimulation: The OBSESS Trial	N/A
Active, not recruiting	`NCT03300947` - Psilocybin for Treatment of Obsessive Compulsive Disorder	Phase 1
Recruiting	`NCT02773082` - Reclaim™ Deep Brain Stimulation (DBS) Therapy for Obsessive-Compulsive Disorder (OCD)	N/A
Not yet recruiting	`NCT06360991` - DBS for Treatment-resistant Obsessive-compulsive Disorder	N/A
Completed	`NCT03605316` - Deep Electrical Neuromodulation in Obsessive-compulsive Disorder