Non-antibiotic Prescribing for Acute Upper Respiratory Tract Infection

Acute Upper Respiratory Tract Infection Clinical Trial

Official title:

Non-antibiotic Prescribing for Acute Upper Respiratory Tract Infection：a Randomized-control Trial

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01930955
• Other study ID #: AURI
• Status: Withdrawn
• Phase: N/A
• Start date: August 1, 2011
• Est. completion date: December 30, 2022

Study information

• Verified date: February 2021
• Source: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Some acute upper respiratory tract infection(AURI) in children is characterized by fever and vomiting,and it is one common reason for visiting a pediatrician. White blood count(WBC) usually increased in this children patients,hence antibiotics are often prescribed properly assumed. In the present study, it was hypothesized that it was not necessary to prescribe amoxicillin for the children.

Description:

After inclusion of eligible children patients,one group was prescribed amoxicillin,and another not.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: December 30, 2022
• Est. primary completion date: December 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Year to 3 Years

Eligibility

Inclusion Criteria:

• Acute upper respiratory tract infection

• Fever

• Vomiting

• Increased white blood cell

Exclusion Criteria:

• 0ther symptoms of digestive system

• Headache

Related Conditions & MeSH terms

• Acute Upper Respiratory Tract Infection
• Communicable Diseases
• Infections
• Respiratory Tract Infections

Intervention

Drug:
• Amoxicillin
ß-lactam antibiotics

Locations

Country	Name	City	State
China	Department of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University	Chongqing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	white cell count	White cell count decreased in 90% participants.	3 days
Primary	fever	Fever stopped or mitigated in 90% participants.	3 days
Secondary	vomiting	Vomiting stopped or mitigated in 90% participants.	2 days