Previously Treated Advanced Colorectal Cancer Clinical Trial
Verified date | May 2018 |
Source | Gachon University Gil Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
To determine the safety and efficacy of second-line treatment with Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the second line treatment of advanced colorectal cancer
Status | Terminated |
Enrollment | 2 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - age over 18 - histologically confirmted advanced colorectal cancer - ECOG PS 0-2 - expected life span more than 3months - normal bone marrow, liver, renal function Exclusion Criteria: - 5-FU, oxaliplatin, irinotecan or Metformin Allergic history - Lactic acidosis, metabolic acidosis - active infection or severe neuropathy |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Gachon University Gil Medical Center | Incheon |
Lead Sponsor | Collaborator |
---|---|
Gachon University Gil Medical Center |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Disease Control Rate | one year | ||
Secondary | Response Rate | one year | ||
Secondary | Overall Survival | one year | ||
Secondary | Number of participants with adverse events | one year | ||
Secondary | Progression Free Survival | one year |