To Assess the Feasibility of CT-derived FFR, WSS and TPF on Coronary Atherosclerotic Plaque Clinical Trial
Official title:
Noninvasive Evaluation of Ischemia Causing Coronary Stenosis, Wall Shear Stress, and Total Plaque Force Using Coronary CT Angiography (CCTA) and Physics-based Analytic Model Derived From Conservation of Energy
| NCT number | NCT01857687 |
| Other study ID # | SNUH CT-FFR WSS TPF |
| Secondary ID | |
| Status | Recruiting |
| Phase | N/A |
| First received | May 16, 2013 |
| Last updated | November 26, 2013 |
| Start date | May 2013 |
To assess the feasibility of CT-derived computed fractional flow reserve (FFRCT), wall shear stress and total plaque force on coronary atherosclerotic plaque and to collect the preliminary data to apply those parameters for the prediction of clinical outcomes in patients with coronary artery stenosis.
| Status | Recruiting |
| Enrollment | 100 |
| Est. completion date | |
| Est. primary completion date | May 2014 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | N/A and older |
| Eligibility |
Inclusion Criteria: - Consecutive patients with available CCTA within 3 months of invasive angiography and invasive imaging methods (IVUS or OCT) Exclusion Criteria: - Poor CT images (unable to reconstruct 3 dimensional coronary artery model) |
Observational Model: Cohort, Time Perspective: Retrospective
| Country | Name | City | State |
|---|---|---|---|
| Korea, Republic of | Seoul National University hospital | Seoul | |
| Korea, Republic of | Seoul National University Hospital | Seoul |
| Lead Sponsor | Collaborator |
|---|---|
| Seoul National University Hospital |
Korea, Republic of,
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| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | CT-derived computed fractional flow reserve | at time of evaulation | No | |
| Secondary | wall shear stress | at time of evaulation | No | |
| Secondary | total plaque force | at time of evaulation | No |