Effect of Medication Reviews Performed in High Risk Patients

Patients in Highest Medication Error Risk Clinical Trial

Official title:

Effect of Medication Reviews in Hospitalized High-risk Patients - a Randomised Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01819974
• Other study ID #: MERIS2
• Status: Recruiting
• Phase: N/A
• First received: March 18, 2013
• Last updated: November 27, 2013
• Start date: April 2013
• Est. completion date: May 2014

Study information

• Verified date: November 2013
• Source: University of Aarhus
• Contact: Dorthe K Bonnerup, Msc
• Phone: +4560472921
• Email: dortbonn[@]rm.dk
• Is FDA regulated: No
• Health authority: Denmark: Danish Dataprotection Agency
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to examine whether a stratified medication review performed in patients at highest risk of experiencing medication errors have impact on numbers of medication errrors during hospitalization.

Description:

Acutely admitted medical patients will be included after admission. After inclusion and randomization the patients will be risk stratified with an existing algorithm according to risk of medication error. The patients in the intervention group will receive a medication review performed by a clinical pharmacist if they are in high medication error risk. Patients in highest medication error risk will recieve a medication review performed by a clinical pharmacologist.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 600
• Est. completion date: May 2014
• Est. primary completion date: November 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Acutely admitted

• >17 years

• Patients being treated with at least one drug at admission

Exclusion Criteria:

• Dying patients

• Suicidal patients

• Intoxicated patients

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Patients in Highest Medication Error Risk

Intervention

Other:
• Stratified medication review
A mediciation review will be performed in patients with high medication error rik. Patients in the highest risk will receive the medication review from a clinical pharmacologist whereas patients assessed in lesser risk will receive the medication review from a clinical pharmacist.

Locations

Country	Name	City	State
Denmark	Aarhus University Hospital	Aarhus

Sponsors (2)

Lead Sponsor	Collaborator
University of Aarhus	Aarhus University Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Medication errors	Medication errors are defined as errors in prescribing that has the potential to harm patients or actually harm patients. This will be assessed by checking the medical records. Two independent experts will do this.	During hospitalization ie. between 8 hours and approximately 20 days	Yes
Secondary	hospital readmissions (all-cause)		3 months after discharge	Yes