Previous Treated Metastatic Non-small Cell Lung Cancer Clinical Trial
Official title:
Randomized Phase II Study of Pemetrexed Versus Gefitinib in Previously Treated Patients With Advanced Non-small Cell Lung Cancer
To compare the efficacy of gefitinib versus pemetrexed as second-line chemotherapy for patients with previous treated non-small cell lung cancer
| Status | Completed |
| Enrollment | 95 |
| Est. completion date | June 2014 |
| Est. primary completion date | June 2014 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Cells pathologically diagnosed as histological or radical surgery or radiation therapy is not possible stage IIIB and stage IV non-small-cell lung cancer patients - second line - ECOG 0~2 - Patients with normal liver function and renal function Exclusion Criteria: - Patients with severe acute infection requiring antibiotic therapy - Patients who have received treatment in other areas of cancer within 5 years - During pregnancy and lactation patients |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Country | Name | City | State |
|---|---|---|---|
| Korea, Republic of | Gachon university Gil Medical Center | Incheon |
| Lead Sponsor | Collaborator |
|---|---|
| Gachon University Gil Medical Center |
Korea, Republic of,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Other | Number of participants with adverse events | 5years | Yes | |
| Primary | Overall response rate | 5 years | No | |
| Secondary | Progression free survival | 5years | No |