Oxygen Level and Safe Emergence From Anesthesia

Focus of Study is Postoperative Pulmonary Atelectacis Clinical Trial

Official title:

Emergence From General Anesthesia With Laryngeal Mask Airway and Increased End-expiratory Pressure Using 30% Oxygen is as Safe as With 100% Oxygen But Reduces the Area of Post Operative Atelectasis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01779076
• Other study ID #: Dnr 2012 / 539
• Status: Completed
• Phase: N/A
• First received: January 28, 2013
• Last updated: January 14, 2018
• Start date: February 2013
• Est. completion date: June 11, 2013

Study information

• Verified date: January 2018
• Source: Region Västmanland
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 59
• Est. completion date: June 11, 2013
• Est. primary completion date: June 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 30 Years to 85 Years

Eligibility

Inclusion Criteria:

• No sign of difficult airway or intubation

• Day case surgery in total intravenous anesthesia with laryngeal mask airway without adding regional anesthesia of plexus brachialis or muscle relaxant.

• Body mass index less than 35.

• American Society of Anesthesiologists physical status (ASA) class I-III

Exclusion Criteria:

• Body mass index 35 or higher

• Increased risk of aspiration

• Obstructive sleep apnea syndrome

• Procedures during surgery making a former easy airway a difficult airway

• Need for opioids after extubation

• Hypothermia

Related Conditions & MeSH terms

• Focus of Study is Postoperative Pulmonary Atelectacis

Intervention

Procedure:
• 30% oxygen

• 100% oxygen

Locations

Country	Name	City	State
Sweden	Västmanlands sjukhus Köping	Köping	Västmanland

Sponsors (1)

Lead Sponsor	Collaborator
Region Västmanland

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Area of atelectasis	The area of atelectasis is investigated by computed tomography of the lungs postoperatively	30 minutes
Secondary	Peripheral oxygen saturation (SpO2)	SpO2 is continuously assessed postoperatively.	3 hours