Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT01759069
Other study ID # Microscope
Secondary ID
Status Recruiting
Phase N/A
First received December 24, 2012
Last updated January 17, 2014
Start date September 2012
Est. completion date December 2015

Study information

Verified date January 2014
Source Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Contact M.H.T. de Ruiter, Drs.
Email m.h.deruiter@amc.nl
Is FDA regulated No
Health authority Netherlands: Medical Ethics Review Committee (METC)
Study type Interventional

Clinical Trial Summary

An endodontic treatment is the standard therapy for teeth with periapical periodontitis. The overall success rate for this treatment is high; 97% of the treated teeth are retained in the oral cavity after 8 years (Salehrabi & Rotstein, 2004). However, there are teeth that have a persistent granuloma because of various reasons and need endodontic retreatment or apical surgery. Overall results in literature for an endodontic retreatment show a success rate of 77%-89% (Ng, Mann, & Gulabivala, 2008; Salehrabi & Rotstein, 2010), the results of apical surgery are more or less similar (von Arx, 2005). Which of the two methods is preferred for failed root canal treatments is dependant on a variety of reasons. (For example an amount of gutta-percha outside the apex of the root is better corrected by apical surgery. Persistent infection as a result of insufficient gutta-percha amounts in a treated root is best treated with an endodontic retreatment.) The overall results in apical surgery have increased the past years due to better preparation of the apical end of the root by the use of an ultrasonic device (de Lange, Putters, Baas, & van Ingen, 2007) and new materials that are used for filling of the rootend e.g. MTA (von Arx, Hanni, & Jensen, 2010)

Objective of the study:

The objective of this study is to assess whether or not apical surgery that is carried out with the help of a microscope has a higher success rate than apical surgery without the use of a microscope. No RCT is found in present literature (Del Fabbro, Taschieri, Lodi, Banfi, & Weinstein, 2009).


Recruitment information / eligibility

Status Recruiting
Enrollment 190
Est. completion date December 2015
Est. primary completion date December 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Peri-apical lesion on one of the teeth, confirmed on radiograph.

- Previous endodontic treatment was more than 6 months earlier.

Exclusion Criteria:

- Root fracture.

- Periodontal origin of apical infection or absence of marginal buccal bone after flap elevation.

- Root perforation.

- No previous endodontic treatment.

- Previous endodontic surgery.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms

  • Effectiveness of Microscope During Apical Surgery in Endodontic Treated Teeth.

Intervention

Procedure:
Surgical treatment with microscope


Locations

Country Name City State
Netherlands Academic Medical Center; Clinic of Oral and Maxillofacial Surgery Amsterdam

Sponsors (1)

Lead Sponsor Collaborator
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Country where clinical trial is conducted

Netherlands, 

Outcome

Type Measure Description Time frame Safety issue
Primary Success is measured by Clinical outcome and radiographic assessment. A radiograph of the treated tooth is made directly post-operative, after 6 months and after 1 year post treatment. Clinical examination is performed at 6 months and 1 year after the operation. 6 months and 1 year No