Patient Harboring Glioblastoma That Will Undergo Surgery Clinical Trial
Official title:
Measurement of Intratumoral Concentration of the Nontoxic Natural Compound Curcumin in Glioblastoma Patients
Measuring the bioavailability of orally administered curcumin in the tumors of glioblastoma patients.
| Status | Completed |
| Enrollment | 15 |
| Est. completion date | May 2013 |
| Est. primary completion date | May 2013 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Patients harboring Glioblastoma - Patient will undergo surgery Exclusion Criteria: - BMI > 30 - Liver and Kidney Function so compromised that medication is prescribed |
Observational Model: Case-Only, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Germany | Department of Neurosurgery, Johann Wolfgang Goethe-University | Frankfurt | Hessen |
| Lead Sponsor | Collaborator |
|---|---|
| Johann Wolfgang Goethe University Hospitals |
Germany,
Senft C, Polacin M, Priester M, Seifert V, Kögel D, Weissenberger J. The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas. BMC Cancer. 2010 Sep 14;10:491. doi: 10.1186/1471-2407-10-491. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Concentration of Curcumin in Glioblastoma | At the time of surgery | At Tumor resection | No |