Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging

Attention-deficit/Hyperactivity Disorder Clinical Trial

— EFMImaging  

Official title:

Executive Functioning and Mindfulness in Adults With ADHD Imaging

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01629914
• Other study ID #: Pro00037192
• Status: Withdrawn
• Phase: N/A
• First received: June 26, 2012
• Last updated: January 30, 2017
• Start date: June 2012
• Est. completion date: January 2013

Study information

• Verified date: January 2013
• Source: Duke University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.

Description:

The broad objective of this proposal is to identify functional neuroanatomical correlates of changes in executive brain functioning prior to and following an 8-week, group-based mindfulness meditation intervention within a group of 10 adults diagnosed with Attention-deficit/hyperactivity disorder (ADHD). Another group of 10 adults diagnosed with ADHD will be placed in the waitlist condition.

Our primary hypothesis is that adults with ADHD in the treatment group will exhibit improved performance on a series of executive functioning tasks and that exposure to task stimuli will correspond to changes in neural functioning following an 8-week, group-based mindfulness intervention. Brain responses will be measured using blood-oxygenation-level-dependent (BOLD) fMRI signal in brain regions associated with emotional and executive processes prior to and following treatment.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: January 2013
• Est. primary completion date: January 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• ages 18-50 years

• meet DSM-IV criteria for ADHD

• intellectual functioning = 80 as assessed by an IQ screener

• generally healthy (i.e., no major medical problems)

Exclusion Criteria:

• major medical condition that would make participation unsafe (e.g., have pacemaker or other metallic implant), uncomfortable (e.g., chronic pain)

• claustrophobic, or abnormally afraid of closed-in places

• current drug use

Related Conditions & MeSH terms

• Attention Deficit Disorder with Hyperactivity
• Attention-deficit/Hyperactivity Disorder
• Hyperkinesis

Intervention

Behavioral:
• Mindfulness Meditation
8-week, group-based mindfulness meditation intervention

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Duke University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change from baseline in blood-oxygenation-level-dependent (BOLD) fMRI signal	Participants will be scanned prior to and following an 8-week group-based mindfulness meditation intervention	baseline and 8-weeks