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The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Optic Neuritis Clinical Trial

Official title:
Collaboration on Neuroimmunology: Question, Understand, Educate, Restore - The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Clinical Trial Summary

This study seeks to determine the biologic causes of inflammation in patients with Transverse Myelitis (TM) Neuromyelitis Optica Spectrum Disorder (NMOSD) and related conditions. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.

Clinical Trial Description

This study seeks to determine the biologic causes of inflammation in patients with Neuromyelitis Optica (NMO), Transverse Myelitis (TM), optic neuritis (ON), related conditions and healthy controls. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions. Patients will agree to share medical records, complete questionnaires and donate samples on a timed basis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01623076
Study type Observational
Source University of Texas Southwestern Medical Center
Contact Jan Cameron-Watts, RN
Phone 214-645-0555
Email jan.cameronwatts@utsouthwestern.edu
Status Recruiting
Phase
Start date June 2012
Completion date June 2025
View Details
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