Acute and Chronic Hepatic Failure With Developing Coma Clinical Trial
Official title:
Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure
| NCT number | NCT01582087 |
| Other study ID # | 12-030 |
| Secondary ID | |
| Status | Terminated |
| Phase | |
| First received | |
| Last updated | |
| Start date | February 2012 |
| Est. completion date | July 24, 2018 |
| Verified date | July 2023 |
| Source | The University of Texas Medical Branch, Galveston |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
The purpose of this study is to understand mechanisms associated with the development of coma during hepatic failure. As of today, those mechanisms are not understood and it is difficult to intervene and prevent coma development which is often associated with mortality. Understanding the mechanism involved, may allow us to prevent coma and develop new therapies to treat this disease.
| Status | Terminated |
| Enrollment | 11 |
| Est. completion date | July 24, 2018 |
| Est. primary completion date | July 24, 2018 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics for chronic or acute hepatic failure will be included in the study. Exclusion Criteria: - Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics that do not have a diagnosis of chronic or acute hepatic failure |
| Country | Name | City | State |
|---|---|---|---|
| United States | The University of Texas Medical Branch | Galveston | Texas |
| Lead Sponsor | Collaborator |
|---|---|
| The University of Texas Medical Branch, Galveston |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | The relationship that exist between a liver undergoing chronic or acute degeneration and hepatic coma. | 8 weeks |