Ovarian Hyperstimulation Syndrome Clinical Trial
Official title:
Endometrial Receptivity After GnRH Agonist Triggering From Final Oocyte Maturation
Conventional luteal phase support after human chorionic gonadotrophin (hCG) triggering in
women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) provides
adequate pregnancy rates and live birth rates, but Ovarian hyperstimulation syndrome (OHSS)
still occurs in 1-3% of the patients. If gonadotropin-releasing hormone agonist (GnRHa) are
used instead of hCG, OHSS does not occur, but clinical results are somehow diminished.
By testing different luteal support protocols on women undergoing GnRHa triggering, the
investigators aim to find out which protocol resembles the most the gene expression profile
observed after hCG triggering and conventional luteal phase support, in order to choose it
as the most adequate in terms of endometrium receptivity and safety (OHSS incidence).
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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