Detection of Helicobacter Pylori Infection by High Resolution Endoscopy

Helicobacter-associated Gastritis Clinical Trial

Official title: Detection of Helicobacter Pylori Infection by Non-magnifying High Resolution Endoscopy is Possible Within the Gastric Corpus

Status Completed

Clinical Trial Summary

Although endoscopic findings of H. pylori have been reported in the literature, there is still some debate over whether H. pylori-related gastritis can be diagnosed via endoscopic features alone. Most studies concluded that it is not possible to diagnose H. pylori-related gastritis on the basis of endoscopic findings. However, the resolution power of endoscopy has greatly improved in recent years and the exact examination of gastric mucosa was possible.

Clinical Trial Description

Our study aimed to achieve the following: (1) describe the H. pylori-related mucosal pattern in the gastric corpus using high-definition endoscopy; (2) evaluate the diagnostic accuracy for H. pylori detection; (3) find the optimal biopsy site for rapid urease test (RUT); (4) validate the inter- and intraobserver agreement in the assessment of endoscopic patterns. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Helicobacter Infections
• Helicobacter-associated Gastritis

• NCT number: NCT01434992
• Study type: Observational
• Source: Kyunghee University Medical Center
• Status: Completed
• Phase: N/A
• Start date: August 2011
• Completion date: January 2012