Non-alcoholic Fatty Liver Disease (NAFLD) Clinical Trial
Official title:
Combined Intensive and Conventional Exercise Intervention of Nonalcoholic Fatty Liver Disease
The prevalence of NAFLD is 50-70% in obese people. A decrease of calorie intake and increase of physical activity are recommended as an effective approach for the prevention and treatment of NAFLD. However, the exercise model for NAFLD intervention is understudied. In the present study we aim to compare the effect of intensive and conventional exercise interventions on NAFLD.
Status | Completed |
Enrollment | 220 |
Est. completion date | December 2013 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 40 Years to 65 Years |
Eligibility |
1. Subjects with NAFLD determined by MRS ; 2. Age 40-65 years old; 3. Waist circumference> 90cm for men and > 85cm for women. |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
China | The First Hospital Affiliated to Xiamen University | Xiamen |
Lead Sponsor | Collaborator |
---|---|
Shanghai Jiao Tong University School of Medicine |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change of intrahepatic triglyceride contents | 12 months | No | |
Secondary | Change of body weight | 12 months | No | |
Secondary | Change of waist circumference | 12 months | No | |
Secondary | Change of body fat | 12 months | No | |
Secondary | Change of abdominal fat | 12 montshs | No | |
Secondary | Change of carotid intima-media thickness | 12 months | No | |
Secondary | Change of cardiovascular risk factors (Blood pressure, lipids, glucose) | 12 months | No | |
Secondary | Change of insulin resistance | 12 months | No |
Status | Clinical Trial | Phase | |
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