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COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined

Rupture of Anterior Cruciate Ligament Clinical Trial

Official title:
COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined

Clinical Trial Summary

Recent studies on molar surgery have shown that a combination of a glucocorticoid and NSAID or COX-2 selective inhibitor gives better pain relief than either of the drugs used separately. The investigators group has also shown that adding dexamethasone on top of a regimen of paracetamol, NSAID and local anesthesia resulted in 45% painfree patients at rest after ambulatory breast cancer surgery.

The goal of this study is to test the NSAID + glucocorticoid concept in ACl repair. The investigators want to evaluate whether a selective COX-2 selective inhibitor or a glucocorticoid or a combination of both drugs, as part of a multimodal analgesic regime, can provide improved pain relief and shorter hospital stay in patients undergoing outpatient ACL surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

  • Rupture of Anterior Cruciate Ligament
Clinical Trial Details
NCT number NCT01361789
Study type Interventional
Source Asker & Baerum Hospital
Contact
Status Completed
Phase Phase 4
Start date January 2004
Completion date December 2009
View Details
See also
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