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Safety Study of High-Dose Ranibizumab for Polypoidal Choroidal Vasculopathy — PEARL2  

Polypoidal Choroidal Vasculopathy Clinical Trial

Official title:
Investigator Sponsored Trial of Polypoidal Choroidal Vasculopathy (PCV) Evaluation Assessing High-Dose Ranibizumab (2.0mg) Prospectively

Clinical Trial Summary

Monthly, continuous anti-vegf therapy for patients presenting with active polypoidal choroidal vasculopathy. Two arms, treatment naive and previously treated with an FDA approved anti-VEGF therapy, will be randomized and dosed with open label 2.0mg ranibizumab.

Clinical Trial Description

Patients will be followed with spectral oct, 4m BCVA, ICG, FA and monthly eye examinations for one year. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01248117
Study type Interventional
Source Retina Consultants of Hawaii
Contact Jacqueline F Shen
Phone (808) 380-8060
Email jshen@retinahi.com
Status Recruiting
Phase Phase 1/Phase 2
Start date November 2010
Completion date February 2013
View Details
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