Increased Intra Ocular Pressure (IOP) Clinical Trial
| NCT number | NCT01241175 |
| Other study ID # | 4286 |
| Secondary ID | |
| Status | Completed |
| Phase | Phase 3 |
| First received | November 15, 2010 |
| Last updated | November 15, 2010 |
| Verified date | March 2009 |
| Source | Shiraz University of Medical Sciences |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Iran: Ministry of Health |
| Study type | Interventional |
The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non ocular surgery
| Status | Completed |
| Enrollment | 0 |
| Est. completion date | |
| Est. primary completion date | |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years to 38 Years |
| Eligibility |
Inclusion Criteria: - 18 to 38 years old - ASA I - scheduled for elective ENT ambulatory surgeries under general anesthesia Exclusion Criteria: - specific major hepatic, renal and cardio-vascular disease - known to have allergic reaction to magnesium sulphate or other drugs , -hypermagnesemia - hypocalcemia - anuria - heart block - pregnancy - any degree of renal insufficiency - digitalised patients - positive history of glaucoma or intra ocular hypertension - refused to participate |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Masking: Double Blind (Caregiver, Outcomes Assessor), Primary Purpose: Prevention
| Country | Name | City | State |
|---|---|---|---|
| Iran, Islamic Republic of | Shiraz University of Medical Sciences | Shiraz | Fars |
| Lead Sponsor | Collaborator |
|---|---|
| Shiraz University of Medical Sciences |
Iran, Islamic Republic of,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Intra ocular pressure | No | ||
| Secondary | blood pressure,heart rate | No |