Hypernatremia Clinical Trial
Official title:
The Use of Enteral Sterile Water Feeds for the Treatment of Hypernatremia in Extremely Low Birth Weight Infants
The improved survival rate of extremely low birth weight(ELBW)infants has resulted in new
fluid and electrolyte problems that have not been encountered previously,in particular
electrolyte imbalance. ELBW infants are especially vulnerable to hypernatremia(serum sodium
value >150 mEq/L). Hypernatremia may be due to rapid dehydration or excessive administration
of intravenous fluids(IV)that contain sodium. The current treatment modality for
hypernatremia is to increase IV fluids above daily requirements.Enteral sterile water
feeds(ESWF)are theorized as an endogenous source of fluids that may decrease elevated
electrolytes such as sodium and potassium in premature infants. By giving ESWF to decrease
elevated electrolytes, there would be less need for large volumes of IVF that contribute to
the co-morbidities of prematurity: bronchopulmonary dysplasia (BPD),intraventricular
hemorrhage(IVH)and patent ductus arteriosus(PDA).
The purpose of this proposed study is to determine whether enteral sterile water feedings is
effective in decreasing the incidence, duration and severity of hypernatremia in ELBW
infants.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06037928 -
Plasma Sodium and Sodium Administration in the ICU
|
||
| Completed |
NCT02926989 -
Intravenous Fluids in Hospitalised Children
|
Phase 4 | |
| Not yet recruiting |
NCT05085223 -
Prospective Analysis Into Development of Hypernatremia in Critically Ill Patients
|
||
| Withdrawn |
NCT01326429 -
Frequency and Origin of Dysnatremias in the Emergency Department
|
N/A | |
| Completed |
NCT01456533 -
Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients
|
N/A | |
| Recruiting |
NCT03658850 -
Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients
|
Phase 2 | |
| Not yet recruiting |
NCT06061783 -
Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water
|
N/A | |
| Completed |
NCT02912299 -
Investigation on Differences in Skin Sodium Content Between Normal Subjects and ICU-patients
|
N/A | |
| Completed |
NCT03752450 -
Prospective Data Analysis of the Development of Hypernatremia in Intensive Care Unit
|
||
| Recruiting |
NCT04949139 -
Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe Hypernatremia
|
Phase 4 | |
| Completed |
NCT00734214 -
Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial
|
Phase 3 | |
| Recruiting |
NCT02449382 -
Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe Hypernatremia
|
N/A | |
| Withdrawn |
NCT01617798 -
Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis
|
N/A | |
| Recruiting |
NCT05818826 -
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
|
Phase 2 | |
| Recruiting |
NCT01299428 -
Evaluation of the Cerebral Oxygenation With Near Infrared Spectrophotometry (NIRS) at the Hypernatremic Dehydration in Newborn
|
N/A | |
| Recruiting |
NCT04265976 -
ED Hypernatremia. Prognostic Factors and Epidemiology.
|
||
| Completed |
NCT03610074 -
Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC)
|
N/A |