Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients

Blood Stem Cell Transplant Failure Clinical Trial

Official title:

Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients at Risk for Respiratory Failure

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01135355
• Other study ID #: PEDSBMT199
• Secondary ID: SU-09222008-1301
• Status: Terminated
• Start date: July 2008
• Est. completion date: January 2011

Study information

• Verified date: June 2024
• Source: Stanford University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of our study is to determine whether a clinically relevant laboratory measurement (of seven specific immunologic biochemicals in the blood) can identify which bone marrow transplant recipients are likely to progress to respiratory failure. Our ultimate goal is to devise a comprehensive and inclusive laboratory test that is effective at determining who is likely to go on to respiratory failure, in order to facilitate early medical intervention.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 26
• Est. completion date: January 2011
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 21 Years

Eligibility

Inclusion Criteria:- Hematopoietic stem cell transplantation (HSCT) for any indication.

• Patients will range from age 0 to age 21. There is no gender restriction. We expect the male to female ratio to end up being about 50/50

• Ability to understand and the willingness to sign a written informed consent document.

Related Conditions & MeSH terms

• Blood Stem Cell Transplant Failure

Locations

Country	Name	City	State
United States	Stanford University School of Medicine	Stanford	California

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Compute median flourescence intensity, standard curves, and estimated pg/mL for each cytokine.		weekly during hospitalization for transplant