Open Trial of Escitalopram Treatment for Male Subjects With Posttraumatic Stress Disorder

Chronic Posttraumatic Stress Disorder Clinical Trial

Official title: Open Trial of Escitalopram Treatment for Male Subjects With Posttraumatic Stress Disorder

Status Completed

Clinical Trial Summary

The primary aim of this pilot study is to test the efficacy of the selective serotonin re-uptake inhibitor, Escitalopram, in the treatment of posttraumatic stress disorder (PTSD) in an open clinical trial.

A secondary aim is to determine whether treatment with escitalopram increases plasma allopregnanolone levels in patients with PTSD and if increases in allopregnanolone levels are correlated with treatment efficacy.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Chronic Posttraumatic Stress Disorder
• Stress Disorders, Post-Traumatic
• Stress Disorders, Traumatic

• NCT number: NCT01024140
• Study type: Interventional
• Source: Northern California Institute of Research and Education
• Status: Completed
• Phase: N/A
• Start date: February 2003
• Completion date: December 2004