Graft Rejection Clinical Trial
Official title:
Randomized Double-blind Placebo-controlled Prevention Trial of Azithromycin in Lung Transplantation.
Preventive treatment with azithromycin reduces the prevalence fo Bronchiolitis Obliterans Syndrome after lung transplantation.
- Prospective, interventional, randomized, double-blind, placebo-controlled trial.
- Clinical setting (tertiary University Hospital).
- Investigator-driven, no pharmaceutical sponsor.
- Lung transplant recipients.
- Add-on of study-drug (placebo or azithromycin) to 'standard of care' (standardized,
routine immunosuppressive and infectious prophylactic protocol).
- 1:1 inclusion ratio (placebo:azithromycin).
- Randomisation at discharge after informed consent.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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